Discuss The Characteristics Of The ABO Gene Locus

1. Which of the following is not a characteristic of the ABO gene locus?
a. dominance/recessiveness b. codominance c. four possible phenotypes d. multiple alleles e. epistasis
2. In a cross in which one parent exhibits blood type O due to the Bombay phenotype, but has alleles IA and i, and the other parent is heterozygous for the Bombay phenotype but has blood type O, what would be the possibility of their first child having blood type O?
a. 1/2 b. 3/16 c. 1/4 d. 0 e. 3/4
3. What is the ratio expected for offspring of a cross between two yellow mice?
a. 3 yellow : 1 agouti b. 2y:1a c:1y:1a d: all yellow e. cannot be determined
4. A couple in which one parent is blood type A and the other is blood type B, and both have normal pigmentation, have a child that is blood type O and has albinism. What is the probability that their next child will have normal pigmentation and blood type A?
3/16, 9/16, 0, 1/16, 1/8
5. In cats, orange coat color is determined by the b allele, and black coat color is determined by the B allele. The heterozygous condition results in a coat pattern known as tortoiseshell. This gene is X-linked.
What are the chances of getting a tortoiseshell female from a cross of a black male and a tortoiseshell female?
A human disorder resulting from a mitochondrial DNA mutation such as MERFF might show various levels of expression among children of a mother with MERFF. This is most likely the result of ________.
conditional mutation, heteroplasmy, maternal effect, genetic anticipation, expressivity
Which of the following is NOT evidence that mitochondria are involved in aging?

Studies in mice have revealed that deletions in mtDNA were common in atrophied muscle fibers, but absent in fibers from normal tissue.

Aging tissues contain mitochondria with increased levels of DNA damage.

Mitochondrial dysfunction has been implicated in a large number of chronic disorders such as type 2 diabetes and neurodegenerative disorders.

The term heteroplasmy refers to mitochondria that are a mixture of normal and abnormal mitochondria.

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