A 67-year-old wom an com plained to her physician of obstinate constipation. The wom an, w ho was su

A 67-year-old wom an com plained to her
physician of obstinate constipation. The wom an, w ho was su ering bone pain
from m etastatic breast cancer, had started a therapy w ith m orphine 2 weeks
previously. Which of the follow ing actions m ost likely m ediated the adverse
e ect of the drug in this patient?

A. Decreased
anal sphincter tone

B. Increased
colonic tone

C. Increased
intestinal peristalsis

D. Increased
re ex response to rectal distention

E.

A 67-year-old wom an com plained to her
physician of obstinate constipation. The wom an, w ho was su ering bone pain
from m etastatic breast cancer, had started a therapy w ith m orphine 2 weeks
previously. Which of the follow ing actions m ost likely m ediated the adverse
e ect of the drug in this patient?

A. Decreased
anal sphincter tone

B. Increased
colonic tone

C. Increased
intestinal peristalsis

D. Increased
re ex response to rectal distention

E. Increased
softening of feces

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