A 61-year-old wom an su ering from the hepatitis B virus (HBV) underwent a follow -up exam ination. She was found to have m ore than 105 HBV DNA copies/m L and alanine transam inase of 210 U/L (norm al 8-20 U/L). Therapy w ith entecavir was started. Inhibition of w hich of the follow ing viral enzym es m ost likely m ediated the therapeutic e ect of the drug in the patients disease? A. DNA polym erase B. Phosphotransferase C. RNA polym erase D. HIV protease E. Thym idine kinase F. Neuram inidase
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