A 48-year-old wom an w ho underwent a liver transplant had been receiving im m unosuppression treatm ent w ith prednisone and cyclosporine. Despite the therapy, a liver biopsy still showed rejection 12 days after surgery, and the therapeutic team decided to substitute tacrolim us for cyclosporine. Which of the follow ing cells represent the m ain site of action of tacrolim us? A. Macrophages B. Dendritic cells C. T-helper cells D. Plasm a cells E. Natural killer cells
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